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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d5efec384090785bf43f661f347d52854d9af7f8cf7853a4031b7a142e31c9' 
  AND token = 'k7q8YbWmqY4Xn/qb6TMcOWBZV6cTiSvaTR31LUz8liU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}