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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a81a1c683bfdc5e5f6d73224494dd1629b274b6cb9103e51735b35d7c7a7875' 
  AND token = 'WRjK4RdXPXnIMPKL6DW3zEhRriUocCk3oVO6gvyhLBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}