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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6678ed006a53f21e90e478b140fd129821cc77a5d89f05683936dced883daeb2' 
  AND token = 'ZM5LQsogExAr5pGdcw8v0FmsHSdxxNAy/MwnQiHa1kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}