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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7170729e90f14291eba25e04b448f46d9108c4b38aa971225193f33b5a3feaa4' 
  AND token = '6Ljydk6GZgp4xoikgE9NGuLe5FDzDqS+khJfdfPIKc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}