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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e3124737d9b4a3c28590d691975b55da9d607245cb5027c9185b90c9da965f5' 
  AND token = '1KvkyqZ/9n5EH5fxqZfmZwIVKi+yTuRlrs6Nf/eb2k0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}