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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '933f945524a4464b63252d104fd2a3aa0ecbf40de0fce8c4d34a2fa82f680308' 
  AND token = 'IxAohWPN5xKX5TZ2105q7X/cWZ9UiJZnMbZDtkj9SmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}