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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74075b283306424c0ec1aa796cd8552e374f2a1af9a3d0ee6e19d4cdff576ec8' 
  AND token = 'fP9QJTZpZRCqoWkJQdNyQPgfRGQ42mJ+6M7OZu3A10w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}