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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d90b1b26a8e0346434ba91d05f6805ca3b4c8f19e20862616549a52392194fa' 
  AND token = 'wucqLPRHWMGGyMfJJ+9JtqIq7pb0OR1RIYTLf2TizXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}