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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14d67c39688dd3a6e29aa5fa5f3fbe3787cde8f6dda3b517272fc80472751849' 
  AND token = '4vF+ofec9GNBTGJ47/CqDMXtGPeZtqkTiwFG1ywbB/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}