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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aac4e25401f981d6e1182c25cf00a5825bbb043c5a347f515059d22619d4e66' 
  AND token = 'n0XUwV2j2LSG6I6wCoHjKzH9rzkc3eBL0iqUC7ktCH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}