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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe48581dfae79665c37623cc5a873343a1b6dd05741544254e501b2b8108d8b2' 
  AND token = 'o34gyzJ4MfCNHm+4y58ZlWivFKenQrq6FTTLSzbaI2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}