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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4c3bb696919c500e1212e3519026af00cf374082082012e033c16ed1bcf56dc' 
  AND token = 'Tsd3iqa9jd8LrfBENY+8YM/oiu60Nmg/bOT2bOOH1QQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}