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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf00c46c04cddc9957b0eae4de6d2a6cdde1efa186dd37a0f482c6496aa0013b' 
  AND token = 'tXvgcXpIqAGZiDHbPjwBdEn1p7OoKHbBwHhivkjY3/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}