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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a44a2937918a07ca686e6bccfdf6649ce6f75083824fc2a911d3bbe312d712ba' 
  AND token = '8V+tOi5TLWxbHd8k8SR2GN1hjwHanjtvgPCKBonHXNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}