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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65dd293031b441a70dcc6ab302ac7c7e9b588d2d4bc0b43039530e3865fdec6e' 
  AND token = '4qZchMOO4TgiY1nfaptqbUT3j0TY1+qrIjmIIDyzNUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}