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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0e2fa127e00ab474066cc9be4cd0353b32bfa50bc30642d5b974f5a2f32e7ab' 
  AND token = 'pg2zwNfFCPIG77aVwqMn7GXuYusL6dCau39LGkuJ6qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}