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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1d49ae190827c7b6deafa2c4e36fe9d46c4a1945f92e2b63ca8ecda5519e3a1' 
  AND token = 'N+u2xDCSRAo0lvyy1DUx8QWfMNCvJtphzqe/BbC7hrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}