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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a800ab3767fd39fb20a23aafc54fe602d92c633f1c457ef0ddde7c3a3778d53e' 
  AND token = 'h6mloYi81MqgzN46e12++qRDVviIptOD9ZePzzpYA40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}