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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e2ba42d24cbe4aead3be0f5820094026cc65cd3d4c85d8edfbaab14b53476d' 
  AND token = 'kDdVdo25w8VegWATD6qpGeHA8VyJxDDIqS/W+IP4Jqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}