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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f1ffb5b5b92e864a59f809931827ee41b728026716c3464e0d648ae8078641' 
  AND token = 'ZHi4BtFYezpJZJIEV+2BB7naXk5FVHH65+I6P8vDrig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}