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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c63e4692de36d14759c0cada3a29bb9ec62e6b988379468a1a2c5f9682d0d14d' 
  AND token = 's7ZuULECQNX/xhVYxDXSF5GqwrQdIwCOSzn22tLrLy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}