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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '416a262345a37b1972be62d978aa0135dbe610763fab38037b6527ef68c70162' 
  AND token = '+97/Fa/nw8MsdcDplLZyBiI+T4461IOtjuXRwO+iSCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}