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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5fde7e221601433a4ee384b4d90968493a763963c5c1465ffe442d63ecc474d' 
  AND token = 'zIbxKgxInya4Sc5JKN6w/9w7ijaTB4xO30aIwtKPv4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}