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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac1bf6f80f4f9f009717e5c4315c7fa56bf020e4fb1898dd98e261e858ea4f7' 
  AND token = 'tCGP9Gel7lb+zugw5A8VVVp4tVV1Abz4XQ95HEJZO5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}