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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed15127c9792b9b2b571c930a602951dd3f0f590eb263f76bb9f0966d34c2207' 
  AND token = 'GTv33rvgeZdfcxpnM7ZgagGhfvrNzW4SaOTWF5OMuAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}