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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '778fa1de3d30343532a1635dd05118f3ffb709a70937c891fd32d886043c71af' 
  AND token = 'v/W2kSLt4EoshZlMb93UQ+8e4l+2sTDNDpsDZugOgIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}