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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e5f9055f4c91b27e594d97b8e1241ff6e2fd42234b0e2cfcea2dad558e7bd4a' 
  AND token = 'oZ/BYGaCcsgzCY4qdSCX9cqz0RX4ATiWYHkTGJmxaIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}