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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a143f8d84fdb1fb6aad5192be4d5e1d4714214f6ba9954aa34af939bedcb45' 
  AND token = 'l/ToKsKcfKrF+17g6uj6G2hOGF7G2D0bMGPgnrhtRgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}