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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e35260e4e61b35e627ee16a9102d167e444e2da2ef9b01403db059188319f22' 
  AND token = 'qHZq7WZXn5tSvqxoZUijUQW2/ja+2FfxDXEO8NQxz9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}