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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf80208a0ae07d946055d69b123acf9c04d449ab1b6a45e5992484b07ed6944e' 
  AND token = 'o3tAH0ekM1BCWYyi7YydeZbmJIQpQquYSckHSGFOw00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}