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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '509727bcbc9a403905d0f80e536d59d671beffafd69ef29b31f67830ed0cd0f4' 
  AND token = 'MTsp0Yat13QBFN26ofG3buyOMOOnQ9H6KsS3D1RIFuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}