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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6855856546b61426f3aee6c6f3b6bc5e93ea0bd1c1a2459eaa176288e25a70d8' 
  AND token = 'tHw2u9mlNCcN+Hd80wmn+7tWYL494hyT/ydZeOfBQT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}