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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f67d0e4e75335da6d6a6df62f4eaa2f4071a386ae08ce3ebb967ca4200bc44' 
  AND token = '0ntNP4w52hRW4zyezWa601QbIN0hGKueDU/zVdKzYmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}