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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b559352100494139043deac55fcf71b404a09ad8ad443d2ad3e3255d98e19de3' 
  AND token = '6sU5c+DJTnJotEUXdWceBPZpHgnqgxBnWHnUVfv61D4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}