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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a43ff3ca0f999e82890c55617523430d27240e6f716adf5f8b1ca5143e4c6067' 
  AND token = '0BKy73suOGa0CxJZl5TxbjNofNeGKjvbQmG+rjMQLUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}