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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a7baef60d59d3942101ffa1505b785a3c55a7bb85481adb7e620a1c402f5ba' 
  AND token = 'Pzx3wCM4tEuRiNi11aS+lnySn15qD/SuTSS/o8nA2VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}