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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d7912214f9b2ffe08ccff06199d6262e7790c16bf17681e8838c65b3538fc1f' 
  AND token = 'WE+JUld2kM1d7mHKBb4oi4RiJhUZ36Qk+8G1/dYNrTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}