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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0b1a8f5b22f9a1fe4bb1453f643f7101e90bcbc292ea73a77aee51db9b2c84' 
  AND token = '+LVVO0mXgacrw1U/s8XpZHgaqNPAtWJt0eh5zC1pXqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}