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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5eacde9a0e3a2b792a3753a21bf8294ba146f72b4278db6a14171e95239fa9c' 
  AND token = 'fWWjkWBbkRam8AfUyVrXkIrcyBEBRBGwLRABPTBYmY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}