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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f2824e43d410b387eede8c6cd0bfe3bffe99c29e2ba3d02e7d4019cb00259b4' 
  AND token = '+QjEiO9GUh4Q2XgMB55JWMnxB3kyKU409mQlmaUQZRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}