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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f7f5a2a285c34075f3147aa5c0080f744e4e05e562ee99fb16ef4ee7ed4a085' 
  AND token = 'PEqe6dCsFZjay2ACJEmjBaIDsXxMw36uM/FR+3u2KEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}