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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66fd58ec8db81230bbacd752cb15d114a6e82cc22443a1d8d25f8b5733e8e41d' 
  AND token = 'kmU7V2oIa+IELq22SP84YPZnzjPVLtzEsm0WnIAQOuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}