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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcdf4ffcb3e33db68fee5448c6cf0dd4dd9bb8b25595e82b75825534dd9449f8' 
  AND token = 'OriBG1vc+vYcntC4UnpzXLUzsQ8T82WZmWbj8iB129Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}