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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd441606684f38931bf64dfcbc604233b0288f0b0f1447032f7563fe98149c1b3' 
  AND token = 'noIEtiBp6L6S5Ori0YcierQ5nMq+5ZDnRUBVuJ62O4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}