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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '254b9ba3e085ff8e91dc3844bb3ff4f4f9c2971e36aff9d5614cb78e7aba3990' 
  AND token = 'm44P2yyUv68UX3JUHdTy1FMcSTtxy6AUsagQixVbvJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}