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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37177133bddd07ce9d21b27904ae1a07d7bd71e900a40e17ddc2ea3e2be9e2c8' 
  AND token = 'eS2WdoOE6VZVoVf0Bkg05sBKC/vfEXISN95/JRY18PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}