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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c3c7b11a0f6c8aeb8b619b5e9571b797775064d37643d4580ae8248b980a709' 
  AND token = 'EqcaVtn3zmF4t1vrqJoBiUHUWNJVdWR2fuSLZ0TYsBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}