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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '115f1ef6a26779d4b6655b9844ac45494af8da6cb66ef841643765268c155259' 
  AND token = '3gU8I4+/CgfykGBH1ShjaaPUSMi4KMf/0/SU5FPSfTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}