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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88088801c7e485fcc6463a447d83e1f50e3db31fdc3ca34e5ab73d78f404a2bb' 
  AND token = 'eMkg9/bz7j7coS/KudA3WXuxkgresod6EfZQVevm4Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}