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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5dfa4af3d2973d52084c63e476b3a1c22b990002f2d867c1532675b29f81936' 
  AND token = 'kDcGS2+7Y/ZQF+SL7MEj8kWtuYjvpF8tcvr90GOtYHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}